Young children may be infected by saliva on the hands of attendants or on toys. Mode of transmission of Epstein–Barr virusĮBV is transmitted by person-to-person spread by the oropharyngeal route via saliva, classically by ‘tongue kissing’. post-transplant lymphoproliferative disorders.nasopharyngeal carcinoma, particularly among groups from China and Taiwan.Burkitt’s lymphoma, which is a monoclonal tumour of B cells that is hyperendemic in highly malarious zones of the world.Only 50 per cent of those infected will develop clinical disease. The infection is most commonly seen in high-school and university students. In developed countries, the age of infection is delayed until older childhood or young adulthood. Occurrence is worldwide and widespread in early childhood in developing countries. Public health significance and occurrence of infectious mononucleosis (glandular fever) Virus can also be isolated from throat swabs or nasopharyngeal aspirates.ĮLISA IgG for nuclear antigen takes 2–3 months to become positive. Polymerase chain reaction (PCR) testing is available for cerebrospinal fluid or tissue specimens through the Victorian Infectious Diseases Reference Laboratory. A full blood examination characteristically shows mononucleosis and a lymphocyte count of 50 per cent or more. Diagnosisĭiagnostic enzyme-linked immunosorbent assay (ELISA) IgG and IgM antibody testing can be conducted on serum. Human herpesvirus 6, cytomegalovirus, toxoplasmosis and acute HIV infection may cause a syndrome resembling glandular fever both clinically and haematologically. A chronic form of the disease is suggested as one of the causes of chronic fatigue syndrome. A variety of uncommon complications have been described, and fatalities are exceedingly rare. The duration of symptoms varies from one to several weeks. In young children, the disease is mild or asymptomatic. Splenomegaly occurs in 50 per cent of patients and jaundice in 4 per cent. Clinical features include fever, generalised lymphadenopathy and a sore throat that is usually an exudative pharyngotonsillitis. ![]() Infectious mononucleosis (glandular fever) is an acute viral infection affecting mainly young adults. Identification of infectious mononucleosis (glandular fever) Clinical features Infectious agent of infectious mononucleosis (glandular fever)Įpstein–Barr virus (EBV) is the causative agent. ![]() Primary school and children’s services centres exclusion is not required. Primary school and children’s services centre exclusion for infectious mononucleosis (glandular fever) Notification requirement for infectious mononucleosis (glandular fever)
0 Comments
Leave a Reply. |